Yeast Infection Skin Rash Treatment

Medically Reviewed by Dany Paul Baby, MD on May 02, 2023
3 min read

Most yeast infections can be treated at home with over-the-counter or prescription medication and will clear up within a week. If some other disease has weakened your immune system, you  should consult a doctor about any new symptoms before attempting self-treatment because of the risk of infection.

  • Vaginal yeast infections
    • Most women can treat vaginal yeast infections at home with nonprescription vaginal creams or suppositories.
    • A single dose of fluconazole (Diflucan) in a tablet also cures most vaginal yeast infections. Fluconazole requires a prescription from your doctor.
  • Thrush
    • For thrush, swish the antifungal agent nystatin around in your mouth , then swallow the liquid. Take care to maintain excellent oral hygiene.
    • All objects put into a child's mouth should be washed or sterilized after each use.
    • Breastfeeding mothers should be evaluated for Candida infection of the breast.
    • If you wear dentures, clean them thoroughly after each use and practice good oral hygiene.
    • Adults and older children have several treatment options which are not available to babies, such as troches (antifungal lozenges) or pills such as fluconazole (Diflucan) to help clear the infection in addition to nystatin.

Skin and diaper rash

  • Clotrimazole (Lotrimin) creams and lotions can be applied to superficial skin infections. Other medications require a prescription and a visit to your doctor.
  • Other antifungal creams, such as ketoconazole (Nizoral), which is available by prescription, is helpful as well.
  • Perlèche, also known as angular cheilitis, is treated with antifungal agents, and often with a mild corticosteroid cream.
  • The affected area should be kept clean and dry.
  • For diaper rashes, frequent diaper changes and the use of barrier creams speed recovery.
  • Intertrigo can benefit from the use of nystatin powder, which decreases the amount of moisture and also acts as an antiyeast agent.

A wide array of treatment options is available to treat candidiasis. Options include creams, lotions, tablets, capsules, troches (lozenges), and vaginal suppositories or creams. Talk to your doctor to find the option that is right for you.

  • Azole medications are a family of antifungal drugs that end in the suffix "-azole." They block the manufacture of ergosterol, a crucial material of the yeast cell wall. Without ergosterol, the yeast cell wall becomes leaky and the yeasts die. Fortunately, ergosterol is not a component of human membranes, and azoles do not harm human cells.
  • Polyene antifungal medications include nystatin and amphotericin B. Nystatin is used for thrush and superficial yeast infections. Doctors reserve amphotericin B for more serious systemic fungal infections. The antifungals work by attaching to ergosterol. These medications then form artificial holes in the yeast wall that cause the yeast to leak and die.