Addison's disease is a rare condition in which the adrenal glands, located near the kidneys, don't make enough of a hormone called cortisol, which helps regulate the body's use of protein, carbohydrates and fat, helps maintain blood pressure and cardiovascular function, and controls inflammation. In another form of the disease, a pituitary gland hormone "turns off" cortisol production. Causes may be infection like HIV, cancer, surgery, radiation therapy, and heredity. Symptoms include fatigue, weakness, weight loss, darkened skin, a craving for salt, and diarrhea. Treatment includes medicine to replace the cortisol and aldosterone the body can't make on its own. Follow the links below to find WebMD's comprehensive coverage about Addison's disease, its causes, symptoms, treatment, and much more.