Medicine is used for an anterior cruciate ligament (ACL) injury to relieve or reduce pain. It also may be used for long-term (chronic) ACL deficiency and during the rehabilitation period. Nonprescription pain medicines such as acetaminophen (Tylenol, for example) or nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, are commonly used.

NSAIDs may cause stomach upset and should be taken with food and a glass of water. They can have side effects and should not be taken with certain other medicines. Let your doctor know what other medicines you are taking. Do not give aspirin to anyone younger than 20 because of the risk of Reye's syndrome.