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Antidepressants for Sleep Problems

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Antidepressant medicines are often prescribed for people who have insomnia. Best results are seen in people who also have depression.1 Doctors often prescribe low doses of certain antidepressants in an attempt to facilitate sleep, even though the medicines have not been well studied for insomnia.

Examples of the antidepressants that might be prescribed for insomnia are amitriptyline and trazodone.

Recommended Related to Sleep Disorders

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Janice used to think her husband's sleepwalking was funny. He fumbled through the dark, often muttered incoherently, and occasionally walked into walls. But she stopped laughing when he made his way to the garage one night and started the car. Experts estimate that sleepwalking afflicts between 1% and 15% of the general population. It's more common in children -- especially those between the ages of 3 and 7 -- than in adults. According to the National Sleep Foundation's 2004 Sleep in America...

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The side effects of these medicines, which may include sexual dysfunction, weight gain, dry mouth and throat, racing pulse, confusion, and disturbed dreams, must be weighed against their potential benefits.

FDA advisories. The U.S. Food and Drug Administration (FDA) has issued:

  • A warning on the antidepressants Paxil and Paxil CR (paroxetine) and birth defects. One new study showed that women who took Paxil during their first 12 weeks of pregnancy had a slightly higher chance of having a baby with birth defects.
  • An advisory on antidepressant medicines and the risk of suicide. Talk to your doctor about these possible side effects and the warning signs of suicide.
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WebMD Medical Reference from Healthwise

Last Updated: November 18, 2013
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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