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Antifibrinolytic agents for hemophilia
Examples
| Generic Name | Brand Name |
|---|---|
| aminocaproic acid | Amicar |
| tranexamic acid | Cyklokapron |
How It Works
Antifibrinolytic agents may be used in specific situations or in combination with clotting factor replacement to treat hemophilia. Antifibrinolytic agents prevent the breakdown of blood clots by neutralizing chemicals in the mucous membranes of the mouth, nose, and urinary tract that break down clots.
Why It Is Used
Antifibrinolytic agents are used to treat nosebleeds (epistaxis) and to help prevent bleeding in the mouth before dental surgery.
How Well It Works
Antifibrinolytic agents effectively prevent bleeding of the mouth when they are combined with a preventive dose of clotting factor.
Side Effects
Possible side effects of antifibrinolytic agents include:
- Upset stomach.
- Headache.
- Flushing.
- Abnormally low blood pressure (hypotension).
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What To Think About
Clotting factors are more effective than antifibrinolytic agents. However, antifibrinolytic medicines may be given instead of or along with clotting factors in certain situations. For example, antifibrinolytic agents may be used to:
- Help prevent bleeding in the mouth, nose, or urinary tract only.
- Help prevent bleeding after dental surgery instead of clotting factor replacement.
Also, unlike clotting factors, antifibrinolytic medication can be taken in pill or liquid form and do not have to be injected.
Complete the new medication information form (PDF)
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WebMD Medical Reference from Healthwise
Last Updated:
March 31, 2010
This information is not intended to replace the advice of a doctor.
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