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Binswanger's Disease

It is possible that the main title of the report Binswanger's Disease is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.


  • Binswanger encephalopathy
  • multi-infarct dementia, Binswanger type
  • subcortical arteriosclerotic encephalopathy, SAE
  • subcortical dementia
  • subcortical ischemic vascular disease
  • vascular dementia, Binswanger type

Disorder Subdivisions

  • None

General Discussion

Binswanger disease is a progressive neurological disorder caused by arteriosclerosis and thromboembolism affecting the blood vessels that supply the white-matter and deep structures of the brain (basal ganglia and thalamus). Most patients experience progressive loss of memory and intellectual abilities (dementia), urinary urgency or incontinence, and an abnormally slow, shuffling, unsteady pattern of walking, usually over a 5-10 year period. Due to their vascular etiology, the symptoms and physical findings associated with Binswanger disease may suddenly worsen due to stroke, stabilize and then improve for a brief time, but the patient's overall condition continues to progress as the blood vessels become increasingly obstructed.


National Association for Continence
P.O. Box 1019
Charleston, SC 29402-1019
United States
Tel: (843)377-0900
Fax: (342)377-0905
Tel: (800)252-3337

Alzheimer's Association
225 N. Michigan Avenue
17th Floor
Chicago, IL 60601
Tel: (312)335-8700
Fax: (866)699-1246
Tel: (800)272-3900
TDD: (312)335-5886

Alzheimer's Disease Education and Referral Center
P.O. Box 8250
Silver Spring, MD 20907-8250
Tel: (301)495-3311
Fax: (301)495-3334
Tel: (800)438-4380

NIH/National Institute on Aging
31 Center Drive, MSC 2292
Building 31
Room 5C27
Bethesda, MD 20892
Tel: (301)496-1752
Fax: (301)496-1072
Tel: (800)222-2225
TDD: (800)222-4225

NIH/National Institute of Neurological Disorders and Stroke
P.O. Box 5801
Bethesda, MD 20824
Tel: (301)496-5751
Fax: (301)402-2186
Tel: (800)352-9424
TDD: (301)468-5981

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223

For a Complete Report:

This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site or email

Last Updated: 3/8/2012
Copyright 1989, 1996, 1997, 2003, 2007, 2009, 2011, 2012 National Organization for Rare Disorders, Inc.

WebMD Medical Reference from the National Organization for Rare Disorders

Last Updated: May 28, 2015
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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