Alterations to the Blood Clotting Process
Medical conditions and medications can alter the process of blood clot formation, making blood clots more or less likely. Some examples include:
Aspirin, Brilinta, Effient, and clopidogrel (Plavix). Drugs that interfere with platelet function, making blood clots less likely.
Warfarin (Coumadin), Eliquis (apixaban), Pradaxa (dabigatran), Xarelto (rivaroxaban). Oral drugs that reduce production of clotting factors, reducing blood clotting.
Heparin. An intravenous or injectable drug that interferes with thrombin, preventing blood clot formation.
Tissue plasminogen activator (tPA). A clot-dissolving drug that activates plasmin, and is occasionally given as a treatment for heart attack or stroke.
Hypercoagulable state. An improper balance between clotting factors and clot-reducing substances that results in increased likelihood of abnormal blood clots.
Hemophilia. A genetic deficiency of certain functioning clotting factors results in poor blood clotting and excessive bleeding.
von Willebrand factor deficiency. A relatively common condition resulting in slow blood clot formation, which is usually mild.