Skip to content
    Font Size
    A
    A
    A

    Cold Agglutinins

    How It Feels

    The blood sample is taken from a vein in your arm. An elastic band is wrapped around your upper arm. It may feel tight. You may feel nothing at all from the needle, or you may feel a quick sting or pinch.

    Risks

    There is very little chance of a problem from having a blood sample taken from a vein.

    • You may get a small bruise at the site. You can lower the chance of bruising by keeping pressure on the site for several minutes.
    • In rare cases, the vein may become swollen after the blood sample is taken. This problem is called phlebitis. A warm compress can be used several times a day to treat this.
    • Ongoing bleeding can be a problem for people with bleeding disorders. Aspirin, warfarin (Coumadin), and other blood-thinning medicines can make bleeding more likely. If you have bleeding or clotting problems, or if you take blood-thinning medicine, tell your doctor before your blood sample is taken.

    Results

    A cold agglutinins blood test is done to check for conditions that cause the body to make certain antibodies called cold agglutinins. The results of the cold agglutinins test is usually reported in titers.

    Normal

    The normal values listed here-called a reference range-are just a guide. These ranges vary from lab to lab, and your lab may have a different range for what's normal. Your lab report should contain the range your lab uses. Also, your doctor will evaluate your results based on your health and other factors. This means that a value that falls outside the normal values listed here may still be normal for you or your lab.

    Cold agglutinins 1
    Normal titer

    Less than 1 to 16 (1:16) at 4 C

    High values

    • High titers of cold agglutinins may be caused by infections, such as pneumonia caused by mycoplasma, mononucleosis, hepatitis C, or other viral infections.
    • High titers of cold agglutinins can cause symptoms when a person is exposed to cold temperatures. These symptoms can include numbness, burning, pain, or pale skin of the fingertips, toes, ears, or nose. Very high titers can mean you have a higher chance of developing blood clots (thromboses) when exposed to cold temperatures.

    WebMD Medical Reference from Healthwise

    Last Updated: September 09, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

    Hot Topics

    WebMD Video: Now Playing

    Click here to wach video: Dirty Truth About Hand Washing

    Which sex is the worst about washing up? Why is it so important? We’ve got the dirty truth on how and when to wash your hands.

    Click here to watch video: Dirty Truth About Hand Washing

    Popular Slideshows & Tools on WebMD

    disciplining a boy
    Types, symptoms, causes.
    fruit drinks
    Eat these to think better.
    embarrassed woman
    Do you feel guilty after eating?
    diabetes supply kit
    Pack and prepare.
    Balding man in mirror
    Treatments & solutions.
    birth control pills
    Which kind is right for you?
    Remember your finger
    Are you getting more forgetful?
    acupuncture needle on shoulder
    10 tips to look and feel good.
    Close up of eye
    12 reasons you're distracted.
    woman biting a big ice cube
    Habits that wreck your teeth.
    pacemaker next to xray
    Treatment options.
    Pink badge on woman chest to support breat cancer
    Myths and facts.

    Pollen counts, treatment tips, and more.

    It's nothing to sneeze at.

    Loading ...

    Sending your email...

    This feature is temporarily unavailable. Please try again later.

    Thanks!

    Now check your email account on your mobile phone to download your new app.

    Women's Health Newsletter

    Find out what women really need.