How It Feels
The blood sample is taken from a vein in
your arm. An elastic band is wrapped around your upper arm. It may feel tight.
You may feel nothing at all from the needle, or you may feel a quick sting or
There is very little chance of a problem from
having a blood sample taken from a vein.
- You may get a small bruise at the site. You can
lower the chance of bruising by keeping pressure on the site for several
- In rare cases, the vein may become swollen after the blood
sample is taken. This problem is called phlebitis. A warm compress can be used
several times a day to treat this.
- Ongoing bleeding can be a
problem for people with bleeding disorders. Aspirin, warfarin (Coumadin), and
other blood-thinning medicines can make bleeding more likely. If you have
bleeding or clotting problems, or if you take blood-thinning medicine, tell
your doctor before your blood sample is taken.
A cold agglutinins blood test is done to
check for conditions that cause the body to make certain
antibodies called cold agglutinins. The results of the
cold agglutinins test is usually reported in titers.
The normal values listed here—called a reference range—are just a guide. These ranges vary from lab to lab, and your lab may have a different range for what's normal. Your lab report should contain the range your lab uses. Also, your doctor will evaluate your results based on your health and other factors. This means that a value that falls outside the normal values listed here may still be normal for you or your lab.
| Normal titer
Less than 1 to 16
(1:16) at 4 C
- High titers of cold agglutinins may be caused
by infections, such as pneumonia caused by mycoplasma,
hepatitis C, or other viral infections.
- High titers of cold
agglutinins can cause symptoms when a person is exposed to cold temperatures.
These symptoms can include numbness, burning, pain, or pale skin of the
fingertips, toes, ears, or nose. Very high titers can mean you have a higher
chance of developing blood clots (thromboses) when exposed to cold