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    Cushing's Syndrome: Corticotropin-Releasing Hormone

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    Topic Overview

    The corticotropin-releasing hormone (CRH) stimulation test helps find out if a pituitary tumor may be causing Cushing's syndrome. It is sometimes done with an inferior petrosal sinus sampling (IPSS) test.

    In these tests, a small tube called a catheter is used. A health professional uses it to collect samples from blood vessels coming from the pituitary gland near the brain and also from a vein in your arm. First you will get a shot of CRH. Then samples of your blood near your pituitary gland and from your arm are taken.

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    If these blood samples show high levels of adrenocorticotropic hormone (ACTH) and cortisol, it usually means that the pituitary gland has a tumor.

    If blood levels of ACTH and cortisol do not rise, your doctor may then look for an adrenal tumor or a cancerous tumor elsewhere in your body.

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    WebMD Medical Reference from Healthwise

    Last Updated: November 14, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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