Efficacy with XIAFLEX®
If you have Dupuytren's contracture and have a cord that can be felt, XIAFLEX® may help reduce contracture and help improve range of motion in the affected hand.*
To find out if XIAFLEX® is right for you, speak with a hand specialist who has experience with all the latest treatment options.
XIAFLEX® May Reduce Contracture
While individual results may vary, XIAFLEX® has been shown to help many patients. It has been shown to help nearly straighten or completely straighten their fingers.
XIAFLEX®-treated patients, compared to placebo-treated patients, showed a greater reduction in contracture at the base of the finger (also known as the MP joint) or in the middle of the finger (also known as the PIP joint).
The proportion of patients who achieved a contracture reduction of the primary joint to 0 to 5 degrees after the first injection was 39% and 1% in Study 1 and 27% and 5% in Study 2 in the XIAFLEX® and placebo groups, respectively.†
- In clinical studies, 44% to 64% of patients receiving
XIAFLEX® (versus 5% to 7% of patients receiving placebo) had
a straight or near-straight finger after up to 3 XIAFLEX®
injections (most patients required 1 or 2 injections).
XIAFLEX® May Improve Range of Motion
XIAFLEX® can also help how much you're able to move your fingers, whether the joint affected by your Dupuytren's contracture is at the base of your finger (also known as the MP joint) or in the middle of your finger (also known as the PIP joint).
XIAFLEX®-treated patients, compared to placebo-treated patients, showed a greater increase from baseline in the range of motion of MP and PIP joints.
- In clinical studies, XIAFLEX® produced a mean increase in range of motion between 40-41 degrees* in MP joints
- In clinical studies, XIAFLEX® produced a mean increase in range of motion between 28-32 degrees* in PIP joints