How XIAFLEX® Works
XIAFLEX® is the first and only FDA-approved nonsurgical treatment option for adults with Dupuytren's contracture when a "cord" can be felt. Your doctor may call this a "palpable cord." That means it is raised above the palm and can be felt easily during an examination.
A cord forms containing excess collagen. Over time, the cord thickens and shortens causing your finger(s) to bend toward the palm.
XIAFLEX® is a medicine that is injected directly into a Dupuytren's cord. This medicine helps break down collagen in the cord that then helps the finger to straighten.
Prescription XIAFLEX® is injected into the Dupuytren's cord by a hand specialist who is experienced in administering XIAFLEX®. If needed, 1 day later, the doctor will extend the treated finger to help break the cord. No incisions are required to administer XIAFLEX®. Up to 3 injections may be given into the cord at
Until XIAFLEX®, adults with Dupuytren's contracture had few options for effective treatment outside of surgery.