Information and Resources
Expectorants for chronic obstructive pulmonary disease (COPD)
Examples
Prescription expectorants
| Generic Name | Brand Name |
|---|---|
| guaifenesin | Fenesin, Humibid L.A., Organidin NR, Sinumist-SR Capsulets |
| iodinated glycerol | Iophen, Organidin, Par Glycerol, R-Gen |
Nonprescription expectorants
| Generic Name | Brand Name |
|---|---|
| guaifenesin | Breonesin, Guiatuss, Halotussin |
Guaifenesin is available in tablet, capsule, or liquid form. Iodinated glycerol is available in liquid form. Your health professional will help you decide which form is best for you.
How It Works
Expectorants may keep mucus from sticking to the airways of the lungs, making it easier to cough up. They are no longer commonly used.
Why It Is Used
Expectorants may be used in chronic obstructive pulmonary disease (COPD) when it is difficult to cough up mucus from the lungs. However, expectorants are not commonly recommended for COPD treatment.1
How Well It Works
Expectorants may bring some relief from symptoms, but there is no evidence that they improve lung function.2
Side Effects
Some people who use guaifenesin experience nausea, vomiting, dizziness, rash, and itching.
Some people who use iodinated glycerol develop a rash. In rare cases, people who use this medication for long periods of time may develop an underactive thyroid gland (hypothyroidism).
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What To Think About
The best way to reduce development of mucus is to stop smoking.
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Citations
Global Initiative for Chronic Obstructive Lung Disease (GOLD) (2005). Executive summary (updated 2005). In Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease. Available online: http://www.goldcopd.com/GuidelinesResources.asp?I1=2&I2=0.
Barnes PJ (2000). Nonantimicrobial aspects of therapy. Seminars in Respiratory Infections, 15(1): 52–58.
WebMD Medical Reference from Healthwise



