Gout is an inflammatory joint disease that causes acute pain and swelling. It is a form of arthritis that develops when uric acid crystals form in and around the joints, commonly affecting the big toe joint.
Raynaud's phenomenon is a condition in which some areas of the body, usually the fingers or toes, have an extreme response to cold temperature or emotional stress. During an attack of Raynaud's, the blood vessels in the affected areas tighten, severely limiting the flow of blood to the skin, causing numbness, tingling, swelling, pain, and pale color.
Infection can cause pain, redness, and swelling that occur with red streaking, heat, fever, or the drainage of pus. An infection often causes tenderness to the touch or pain with movement at the site of the infection.