Fungal Infections: Risks of Oral Antifungals

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Before you decide to take an oral antifungal medicine to treat a fungal infection such as athlete's foot or a fungal nail infection, you and your doctor will want to consider the possible risks. Depending on the medicine and your risk factors, some antifungal medicines may:

Affect liver or kidney function.
Cause liver damage or failure, particularly when combined with alcohol or certain medicines.
Weaken the heart's ability to contract, leading to heart failure.¹
Cause dangerous side effects when combined with many different common medicines.

During oral antifungal treatment, your doctor may require blood tests to check your kidney and liver function.

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Possible mild side effects caused by antifungal medicines include stomach upset, headaches, and skin rash.

WebMD Medical Reference from Healthwise

Last Updated: July 20, 2010

This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.