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Glomerular filtration rate (GFR)

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Topic Overview

Glomerular filtration is the process by which the kidneys filter the blood, removing excess wastes and fluids. Glomerular filtration rate (GFR) is a calculation that determines how well the blood is filtered by the kidneys, which is one way to measure remaining kidney function.

Glomerular filtration rate is usually calculated using a mathematical formula that compares a person's size, age, sex, and race to serum creatinine levels. A GFR under 60 mL/min/1.73 m² may indicate kidney disease-the lower the GFR number, the worse the kidney function. This number is an estimate. It may not be a good measure of kidney health in some people, such as the very young or very old, amputees, or obese people.

Recommended Related to Kidney Disorders

Kidney Dialysis

Your kidneys help filter waste, excess fluid, and toxins from your blood. They are also important for blood cell production and bone health. If kidneys don't work properly, harmful substances build up in the body, blood pressure can rise, and too much fluid can collect in the body's tissues, which leads to swelling, called edema. If your kidneys fail, you will need a life-saving treatment called dialysis to take over their job.

Read the Kidney Dialysis article > >

For more information on kidney disease, see the topic Chronic Kidney Disease.

WebMD Medical Reference from Healthwise

Last Updated: August 12, 2008

This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.