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Information and Resources
Malignant Hyperthermia
Important
It is possible that the main title of the report Malignant Hyperthermia is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Synonyms
- Hyperpyrexia
Disorder Subdivisions
- None
General Discussion
Malignant Hyperthermia (MH) is a pharmacogenetic channelopathy affecting skeletal muscle. When MH-susceptible individual are given potent inhalational agents (halothane, sevoflurane, desflurane, etc.) and/or succinylcholine, they can develop a hypermetabolic state that can rapidly progress to a high temperature, muscle rigidity, cardiac arrest, and ultimately may lead to death.
Resources
Malignant Hyperthermia Association of the United States
11 East State Street
PO Box 1069
Sherburne, NY 13460-1069
USA
Tel: (607)674-7901
Fax: (607)674-7910
Email: info@mhaus.org
Internet: http://www.mhaus.org
North American Malignant Hyperthermia Registry
Penn State University
Dept. of Anesthesiology
P.O. Box 850
Hershey, PA 17033-0850
USA
Tel: (412)692-6390
Fax: (412)692-8658
Tel: (888)274-7899
Email: bwb@pitt.edu
Internet: http://www.mhreg.org
NIH/National Institute of General Medical Sciences
45 Center Drive MSC 6200
Bethesda, MD 20892-6200
Tel: (301)496-7301
Fax: (301)402-0224
Email: info@nigms.nih.gov
Internet: http://www.nigms.nih.gov/
Malignant Hyperthermia Investigation Unit
Toronto General Hospital
200 Elizabeth Street
CCRW-2, Room ES3-403A
Toronto
Ontario, Intl M5G 2C4
Canada
Tel: (416) 340-3128
Fax: (416) 340-4960
Email: info@mhacanada.org
Internet: http://www.mhacanada.org
MUMS National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
USA
Tel: (920)336-5333
Fax: (920)339-0995
Tel: (877)336-5333
Email: mums@netnet.net
Internet: http://www.netnet.net/mums/
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223
Email: http://rarediseases.info.nih.gov/GARD/EmailForm.aspx
Internet: http://rarediseases.info.nih.gov/GARD
Madisons Foundation
PO Box 241956
Los Angeles, CA 90024
Tel: (310)264-0826
Fax: (310)264-4766
Email: getinfo@madisonsfoundation.org
Internet: http://www.madisonsfoundation.org
Neuroleptic Malignant Syndrome Information Service, Inc.
PO Box 1069
11 East State Street
Sherburne, NY 13460
Tel: (607)674-7920
Fax: (607)674-7910
Email: info@nmsis.org
Internet: http://www.nmsis.org
For a Complete Report:
This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org
Last Updated: 4/10/2009
Copyright 1984, 1988, 1989, 1990, 1992, 1999, 2005, 2009 National Organization for Rare Disorders, Inc.
WebMD Medical Reference from the National Organization of Rare Disorders
Last Updated:
October 07, 2011
This information is not intended to replace the advice of a doctor.
Healthwise disclaims any liability for the decisions you make based on this
information.
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