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Medicines and Other Substances That Can Cause Symptoms of Depression

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Many medicines and other substances can cause changes in how we feel. Medicines that can cause symptoms of depression include:

Symptoms of depression can also be caused by the use of or withdrawal from alcohol and illegal drugs, such as cocaine, amphetamines (methamphetamines, crystal meth, or crack), heroin, and cannabis (marijuana).

Did You Know?

Under the Affordable Care Act, many health insurance plans will cover preventive mental health services, including screening tests for depression and alcohol misuse, at no cost to you. Learn more.

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If you think that your feelings of depression may be caused by a medicine:

  • Call the doctor who prescribed the medicine, to find out whether you should stop taking it or take a different one.
  • If you are taking a nonprescription medicine, stop taking it. Call your doctor if you feel you need to continue taking the medicine.
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WebMD Medical Reference from Healthwise

Last Updated: January 11, 2013
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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