nephrotic syndrome depends on the cause and the age of
the person who has the condition. Medicines, changes in diet, and care for
other conditions, such as
diabetes or high blood pressure, are all possible
treatments for this syndrome. These treatments may reverse, slow, or prevent
further kidney damage.
Most children who have nephrotic syndrome
do well with treatment and have a normal life expectancy.
Doctors define complete recovery as living without symptoms or
treatment for more than 2 years.
nephrotic syndrome depends on the cause of the disease
and may include:
First treatments can
last from 6 to 15 weeks, often longer in adults. Depending on how severe your
symptoms are or whether they return, ongoing treatment may be needed for
months to years, or even for the rest of your life.
Ongoing treatment for
nephrotic syndrome and complications of the disease
- Daily or alternate-day
prednisone, if nephrotic syndrome returns.
- Cyclophosphamide, cyclosporine, or mycophenolate
mofetil, when treatment with corticosteroids is not successful.
- Steps to lower blood pressure, including medicine, a healthier
diet, and exercise. Untreated
high blood pressure increases your risk for
heart attack. For more information, see the topics
High Blood Pressure,
Coronary Artery Disease, and
- Changes in
diet to replace nutrients lost through the urine,
reduce fluid buildup in the body, and reduce the risk of complications. Some
doctors prescribe a diet that limits protein, salt (sodium), and fats but is
high in carbohydrates. The amount of protein allowed may vary, depending on
- Anticoagulants, such as warfarin
(Coumadin) or heparin, to treat blood clots if they form.
treatment of infections with antibiotics.
- Vaccinations with a
pneumococcal vaccine(What is a PDF document?),
chickenpox (varicella) vaccine, and a yearly flu shot.
Vaccination is not recommended until nephrotic syndrome has responded to
treatment with corticosteroids.
and vitamin D supplements to protect your bones and help prevent
osteoporosis during long-term corticosteroid treatment
(for example, prednisone).
You may need emotional support during treatment for
nephrotic syndrome. If you or your child has nephrotic syndrome and you are
having a hard time handling treatment or the severity of your child's
condition, it may help to talk with a doctor or seek
Treatment if the condition gets worse
nephrotic syndrome is unsuccessful. If this occurs,
you may develop
chronic kidney disease. Your doctor may recommend that
peritoneal dialysis, or consider a
kidney transplant. For more information, see the topic
Chronic Kidney Disease.
Clinical trials are ongoing to test more effective
medicines for the treatment of steroid-resistant (relapsing) nephrotic
syndrome. If treatment has not successfully controlled your nephrotic syndrome,
ask your doctor about clinical trials. To take part in a clinical trial, you
may need to travel to a large treatment center.