In general, whether you take medications for your cold or not, you'll get better in about a week. Rest and liquids are the best treatment for a cold. Antibiotics will not help. However, nonprescription medications help relieve some cold symptoms, such as nasal congestion and cough.

Allergy symptoms, especially runny nose, often respond to antihistamines. Antihistamines are also found in many cold medications, often together with a decongestant. However, the value of antihistamines in treating cold symptoms is under debate.

Decongestants

Decongestants make breathing easier by shrinking swollen mucous membranes in the nose, allowing air to pass through. They also help relieve runny nose and postnasal drip, which can cause a sore throat.

Decongestants can be taken orally or used as nose drops or sprays. Oral decongestants (pills) are probably more effective and provide longer relief, but they cause more side effects. Pseudoephedrine (the active ingredient in products such as Sudafed) is an oral decongestant. In some states, medicines containing pseudoephedrine (such as Sudafed) are kept behind the pharmacist's counter or require a prescription. You may need to ask the pharmacist for it or have a prescription from your doctor to buy the medicine.

Sprays and drops provide rapid but temporary relief. Nasal sprays containing phenylephrine (such as Neo-Synephrine) are effective. Sprays and drops are less likely to interact with other drugs than oral decongestants are. Saline nose drops are not decongestants but may help keep nasal tissues moist so the tissues can filter air.

Decongestant precautions

• Do not give cold medicines or oral decongestants to a child younger than 2 unless your child’s doctor has told you to. If your child’s doctor tells you to give a medicine, be sure to follow what he or she tells you to do. Nonprescription cold medicines have not been proven effective for preschool children.
• Do not use medicated nasal sprays or drops more than 3 times a day or for more than 3 days in a row. Continued use will cause a "rebound effect," in which your mucous membranes swell up more than before you used the spray.
• Drink extra fluids when taking cold medications.
• Decongestants can cause problems for people who have certain health problems, such as heart disease, high blood pressure, glaucoma, diabetes, or an overactive thyroid. Decongestants may also interact with some drugs, such as certain antidepressants and high blood pressure medications. Read the package carefully or ask your pharmacist or doctor to help you choose the best decongestant for you.
• If you are pregnant, check with your doctor or pharmacist before using a decongestant.

Cough preparations

Coughing is your body's way of getting foreign substances and mucus out of your respiratory tract. Coughs are often useful, and you shouldn't try to eliminate them. Sometimes, though, coughs are severe enough to impair breathing or prevent rest.