Skip to content

    OCD Medicines Other Than SSRIs

    Font Size
    A
    A
    A

    Topic Overview

    Although selective serotonin reuptake inhibitors (SSRIs) are most often used to treat obsessive-compulsive disorder (OCD), there are other medicines that may be used or added to SSRI medicines for OCD.

    Risperidone (Risperdal) is one such medicine that sometimes is added to SSRI treatment of OCD. Risperidone has been shown to reduce depression and anxiety symptoms in people with OCD whose symptoms have not responded to an SSRI alone.1 Risperidone is an antipsychotic drug that can cause some negative side effects, such as:

    Recommended Related to Mind, Body, Spirit

    WebMD Checkup: Joan Didion

    Your best-selling book The Year of Magical Thinking chronicles your grief following the loss of your husband, John. What surprised you most about grieving? I did not expect the degree of derangement-both physiological and mental. An example of the latter: Two weeks after John died, when I filled out a hospital form for the autopsy report, I gave not my own address but that of an apartment in which we had lived for the first four or five months of our marriage, in 1964. Is there something...

    Read the WebMD Checkup: Joan Didion article > >

    The makers of Risperdal (risperidone) have recently issued a warning that there may be an increased risk of stroke among older adults who take this medicine. Discuss this risk with your doctor before trying Risperdal (risperidone).

    Another medicine that might be added to SSRI treatment of OCD is clonazepam. Clonazepam is considered both an anticonvulsant and a benzodiazepine medicine. It sometimes is used to treat anxiety disorders as well as Tourette's disorder (a tic disorder). Research is ongoing to find out how effective it is to add clonazepam to an SSRI to treat OCD.

    If other mental health disorders (such as depression) are present along with OCD, it may be necessary to treat the disorders at the same time with additional medicines that may include:

    The U.S. Food and Drug Administration (FDA) has issued a warning on anticonvulsant and mood stabilizer medicines and the risk of suicide and suicidal thoughts. The FDA does not recommend that people stop using these medicines. Instead, people who take anticonvulsant or mood stabilizer medicine should be watched closely for warning signs of suicide. People who take anticonvulsant or mood stabilizer medicine and who are worried about this side effect should talk to a doctor.

    See Drug Reference for more information about these medicines. (Drug Reference is not available on all systems.)

    1

    WebMD Medical Reference from Healthwise

    Last Updated: November 14, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
    Next Article:

    OCD Medicines Other Than SSRIs Topics

    Hot Topics

    WebMD Video: Now Playing

    Click here to wach video: Dirty Truth About Hand Washing

    Which sex is the worst about washing up? Why is it so important? We’ve got the dirty truth on how and when to wash your hands.

    Click here to watch video: Dirty Truth About Hand Washing

    Popular Slideshows & Tools on WebMD

    disciplining a boy
    Types, symptoms, causes.
    fruit drinks
    Eat these to think better.
    embarrassed woman
    Do you feel guilty after eating?
    diabetes supply kit
    Pack and prepare.
    Balding man in mirror
    Treatments & solutions.
    birth control pills
    Which kind is right for you?
    Remember your finger
    Are you getting more forgetful?
    sticky notes on face
    10 tips to clear your brain fog.
    Close up of eye
    12 reasons you're distracted.
    woman biting a big ice cube
    Habits that wreck your teeth.
    apple slices with peanut butter
    What goes best with workouts?
    Pink badge on woman chest to support breat cancer
    Myths and facts.

    Women's Health Newsletter

    Find out what women really need.