Skip to content
My WebMD Sign In, Sign Up

Prerenal Acute Kidney Injury

Font Size

Topic Overview

Prerenal acute kidney injury (AKI), also called acute renal failure, occurs when a sudden reduction in blood flow to the kidney camera.gif (renal hypoperfusion) causes a loss of kidney function. In prerenal acute kidney injury, there is nothing wrong with the kidney itself.

Prerenal acute kidney injury is the most common type of acute kidney injury. It can be a complication of almost any disease, condition, or medicine that causes a decrease in the normal amount of blood and fluid in the body.

Causes of prerenal acute kidney injury include:

  • Severe blood loss and low blood pressure related to major cardiac or abdominal surgery, severe infection (sepsis), or injury.
  • Medicines that interfere with the blood supply to the kidneys. Medicines such as ACE inhibitors and common pain medicines (NSAIDs) commonly cause prerenal acute kidney injury in people who already have an increased risk for kidney problems.
  • Severe dehydration caused by excessive fluid loss.
  • Severe burns.
  • Pancreatitis and liver diseases, such as cirrhosis, that create fluid shifts in the abdomen.

Treatment focuses on correcting the cause of the prerenal acute kidney injury. Depending on the cause, the condition often reverses itself within a couple of days after normal blood flow to the kidneys has been restored. But if it is not reversed or treated successfully and quickly, prerenal acute kidney injury can cause tissue death in the kidneys and lead to intrinsic (intrarenal) acute kidney injury.

1

WebMD Medical Reference from Healthwise

Last Updated: May 08, 2013
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
Next Article:

Prerenal Acute Kidney Injury Topics

Hot Topics

WebMD Video: Now Playing

Click here to wach video: Dirty Truth About Hand Washing

Which sex is the worst about washing up? Why is it so important? We’ve got the dirty truth on how and when to wash your hands.

Click here to watch video: Dirty Truth About Hand Washing

Popular Slideshows & Tools on WebMD

feet
Solutions for 19 types.
row of colored highlighter pens
Recognizing symptoms.
build a better butt
Check your BMI.
man with indigestion
How to build a better butt.
MS Overview
How to identify that bite.
stressed working woman
What to watch for.
brain scan with soda
Tips to kick the habit.
fat caliper
Tips for living better.
Woman running
And how to fix them?
lone star tick
Check your BMI.
young woman in sun
What Do Your Dreams Say About You?
Girl drinking orange juice
How to keep yours at bay.

Women's Health Newsletter

Find out what women really need.