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You want more power for your morning workout, an afternoon lift during a long workday, or while you cheer your kids on the soccer field. Will a supplement do that?

Some will make a difference. But it’s best to talk with your doctor first. She can see it’s OK for you to take.

The most common supplements people turn to for energy include:

Caffeine. It revs up your metabolism and makes you feel like you have more physical and mental energy. If you just want a slight pick-me-up, Kathi Kemper, MD, director of the Center for Integrative Health and Wellness at Ohio State University, recommends caffeine from natural sources, such as a cup of coffee or tea, rather than supplements.

Guarana. This herb contains caffeine. Some studies show that it can help young adults with mental strain. But if you already get caffeine from other sources, such as coffee, be careful not to overdo it as it can disturb your sleep.

Ginseng. It may improve mood and energy. You can try it, but keep your expectations in check. Kemper notes that because it’s a relatively expensive herb, some products don’t contain much ginseng and instead have more filler ingredients. 

Vitamin B12. “Your internal energy factories just don’t work as well without it,” Kemper says.

If you already take a multivitamin, you probably already get the recommended daily dose, so you don’t need an extra supplement. And unless you are low on B12, science doesn’t show it will give you an extra boost.

Are you vegan (you eat no meat, dairy, or other animal products)? Then you may need B12 supplements, because only animal foods have vitamin B12 naturally.

Coenzyme Q10. Your cells need this antioxidant to make energy. It’s harmless, but there is no strong evidence that it curbs fatigue, Kemper says.

More Things You Can Do to Get Energy

“Technically, energy comes from calories,” Kemper says. So you might want to have a healthy snack, like almonds and fruit, or yogurt with granola.

It’s also a good idea to drink something, because we often feel tired when we’re actually thirsty.

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