Prolotherapy involves injecting a substance into the body to promote
the growth of normal cells, tissues, or organs. There are three types of
prolotherapy. The type used to treat joint pain is called inflammatory
In inflammatory prolotherapy, a sugar water solution (dextrose) is
injected into a weakened ligament near where the ligament attaches to the bone.
The injection is intended to cause inflammation. The body responds to the
inflammation by increasing blood flow to the area and stimulating the ligament
to repair itself. Usually, a person would have a series of 4 to 6 treatments,
each about 2 weeks apart.
When you've got back pain, one of the best questions you can ask is, "Why is it happening?" That can be the first step to helping the problem.
Common causes for back pain include:
Muscle and ligament injuries. These are the most common causes of back pain. Shoveling snow or helping a friend move her couch can sometimes overstretch the muscles or ligaments. You can wind up with strains or sprains. Most of these injuries heal in a few days to weeks.
A review of several
studies suggests that prolotherapy injections alone may not be helpful for
chronic low back pain. But they may reduce pain and help you be more active if
they are used in addition to other treatment such as exercise and spinal
manipulation.1 A separate review concludes that prolotherapy may not work.2
The biggest risk in prolotherapy treatment is nerve damage
from an injection placed too close to a nerve. There are also no established
guidelines for the procedure at this time. Most pain experts do not recommend prolotherapy for low back pain.