Quinidine for Malaria
How It Works
Quinidine prevents the development of
malaria parasites in the blood.
is given through a needle directly into a vein (intravenously,
or IV) for a maximum of 7 days. A person receiving quinidine is usually treated in a hospital, because his or her heart needs to be monitored during treatment.
Why It Is Used
You use quinidine for severe malaria
- You cannot take oral antimalarial
- You have serious complications (such as
heart failure or
- The percentage of red
blood cells infected (density of parasites) is greater than 5%, and the
infection is very severe.
How Well It Works
Quinidine is effective in the
treatment of severe Plasmodium falciparum
All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.
Here are some important things to think about:
- Usually the benefits of the medicine are more important than any minor side effects.
- Side effects may go away after you take the medicine for a while.
- If side effects still bother you and you wonder if you should keep taking the medicine, call your doctor. He or she may be able to lower your dose or change your medicine. Do not suddenly quit taking your medicine unless your doctor tells you to.
Common side effects of this medicine include:
- Very low levels of sugar in the blood (hypoglycemia).
- Nausea and upset stomach.
- Headache and blurred
- Ringing in
the ears and temporary loss of hearing.
- An abnormal
See Drug Reference for a full list of side effects. (Drug
Reference is not available in all systems.)
What To Think About
You will take oral medicines to treat the malaria as soon as you stop taking
intravenous (IV) quinidine.
In the United States, intravenous quinidine is used,
because intravenous quinine is not available.
Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.
Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.
Primary Medical Reviewer
||E. Gregory Thompson, MD - Internal Medicine
Specialist Medical Reviewer
||W. David Colby IV, MSc, MD, FRCPC - Infectious Disease
||April 11, 2013