Having a blood transfusion in
the past 4 months can cause a
false-negative test result because of the normal
hemoglobin from the blood donor.
What To Think About
Most states routinely do a sickle cell blood
test on all newborns.
If you have a family history of sickle cell
disease, you may be advised to have a blood test to determine whether you carry
the sickle cell trait. If you have sickle cell trait or sickle cell disease,
you may choose
genetic counseling before deciding to have
under 6 months of age may have false-negative results because they have more
hemoglobin F (fetal hemoglobin) in their blood.
In the United
States, sickle cell disease mainly affects African Americans and Latin
Other Places To Get Help
Centers for Disease Control and Prevention (CDC):
National Center on Birth Defects and Developmental Disabilities
1600 Clifton Road, MS E-87
NCBDDD aims to find the cause of and prevent birth
defects and developmental disabilities. This agency works to help people of all
ages with disabilities live to the fullest. The website has information on
many topics, including genetics, autism, ADHD, fetal alcohol spectrum
disorders, diabetes and pregnancy, blood disorders, and hearing loss.
U.S. Preventive Services Task Force (2007). Screening for Sickle Cell Disease in Newborns. Available online: http://www.ahrq.gov/clinic/uspstf/uspshemo.htm.
Other Works Consulted
Chernecky CC, Berger BJ (2008). Laboratory Tests and Diagnostic Procedures, 5th ed. St. Louis:
Fischbach FT, Dunning MB III, eds. (2009).
Manual of Laboratory and Diagnostic Tests, 8th ed.
Philadelphia: Lippincott Williams and Wilkins.
Pagana KD, Pagana TJ (2010). Mosby?s Manual of Diagnostic and Laboratory Tests, 4th ed. St. Louis: Mosby Elsevier.