Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Font Size



There’s no known treatment for smallpox. Getting the vaccine within 3 to 4 days of contact with the virus may make the disease less severe or maybe help prevent it.

Beyond that, medical care aims to ease symptoms like fever and body aches, and control any other illnesses that a person can get when their immune system is weak. Antibiotics can help if someone gets a bacterial infection while they have smallpox.

Scientists are still looking for antiviral medicines that could treat the disease. The drug cidofovir has worked well in early studies.

Prevention: The Smallpox Vaccine

Scientists use the cousin virus to variola -- the vaccinia virus – to make the smallpox vaccine, because it poses fewer health risks. The vaccine prompts the body's immune system to make the tools, called antibodies, it needs to protect against the variola virus and help prevent smallpox disease.

No one knows for sure how long the smallpox vaccine protects people from the disease. Some experts believe it lasts for up to 5 years and wears off over time. Since it may not give lifelong protection, anyone vaccinated years ago as a child could be at risk of future infection by the variola virus. The only people known to be immune for life are those who have had smallpox and survived.

The World Health Organization and its member countries keep an emergency stockpile of the smallpox vaccine. It’s rarely used today, except for those few people who are around the variola virus, such as laboratory researchers working with variola and viruses like it.

Risks of the Vaccine

Some of its side effects can be dangerous, especially for people with weak immune systems. They can range from skin reactions to a serious nervous system condition called encephalitis, which can lead to convulsions, coma, and death. But these side effects are very rare. Based on historical data, for every 1 million people vaccinated for smallpox, one to two people died from a bad reaction.

Some people would have a higher risk of a reaction to the vaccine, like:

  • Women who are pregnant or breastfeeding
  • People with skin disorders such as eczema
  • People with a weak immune system due to a medical condition like leukemia or HIV
  • People on medical treatments, such as for cancer, that make the immune system weak

Hot Topics

WebMD Video: Now Playing

Click here to wach video: Dirty Truth About Hand Washing

Which sex is the worst about washing up? Why is it so important? We’ve got the dirty truth on how and when to wash your hands.

Click here to watch video: Dirty Truth About Hand Washing

Popular Slideshows & Tools on WebMD

disciplining a boy
Types, symptoms, causes.
Remember your finger
Are You Getting More Forgetful?
fruit drinks
Eat these to think better.
No gym workout
Moves to help control blood sugar.
acupuncture needle on shoulder
10 tips to look and feel good.
Close up of eye
12 reasons you're distracted.
birth control pills
Which kind is right for you?
embarrassed woman
Do you feel guilty after eating?
Epinephrine Injection using Auto-Injector Syringe
Life-threatening triggers.
woman biting a big ice cube
Habits that wreck your teeth.
pacemaker next to xray
Treatment options.
caregiver with parent
10 tips for daily life.

Pollen counts, treatment tips, and more.

It's nothing to sneeze at.

Loading ...

Sending your email...

This feature is temporarily unavailable. Please try again later.


Now check your email account on your mobile phone to download your new app.

Women's Health Newsletter

Find out what women really need.