Skip to content

Treating Drug-Resistant Tuberculosis

Font Size

Topic Overview

People infected with tuberculosis (TB) bacteria that are antibiotic-resistant need special treatment programs. People with a weakened immune system are more likely to get drug-resistant TB. These include people infected with HIV or people who have had an organ transplant.

Treatment usually involves at least four medicines.1

Recommended Related to Lung Disease/Respiratory Problems

Primary Intestinal Lymphangiectasia

Important It is possible that the main title of the report Primary Intestinal Lymphangiectasia is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Read the Primary Intestinal Lymphangiectasia article > >

  • A treatment program using four to six medicines appears to be best. The choice of medicines depends on the results of sensitivity testing.
  • Most treatment programs involve isoniazid, rifampin, and pyrazinamide, along with one to three second-choice medicines.
  • Second-choice medicines used to treat drug-resistant TB usually have more side effects than the first-choice medicines. Second-choice medicines include streptomycin, capreomycin, ethionamide, kanamycin, ofloxacin, para-aminosalicylic acid, and rifabutin.
  • It is very important to take every dose of medicine. So directly observed therapy (DOT) usually is done. During DOT, a health professional watches you take every dose of medicine.
  • Treatment is continued until TB bacteria can no longer be found in two sputum samples taken a month apart. This may take 18 months or longer in people with multidrug-resistant TB (MDR-TB).

Some TB bacteria have become resistant to all of the antibiotics that are commonly used to treat TB. This is sometimes called totally resistant tuberculosis (TDR-TB).2 A TB infection of this type is very difficult to treat.

1

WebMD Medical Reference from Healthwise

Last Updated: April 04, 2013
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
Next Article:

Treating Drug-Resistant Tuberculosis Topics

Hot Topics

WebMD Video: Now Playing

Click here to wach video: Dirty Truth About Hand Washing

Which sex is the worst about washing up? Why is it so important? We’ve got the dirty truth on how and when to wash your hands.

Click here to watch video: Dirty Truth About Hand Washing

Popular Slideshows & Tools on WebMD

disciplining a boy
Types, symptoms, causes.
psoriasis
What it looks like.
fruit drinks
Eat these to think better.
No gym workout
Moves to help control blood sugar.
acupuncture needle on shoulder
10 tips to look and feel good.
Close up of eye
12 reasons you're distracted.
Epinephrine Injection using Auto-Injector Syringe
Life-threatening triggers.
woman biting a big ice cube
Habits that wreck your teeth.
embarrassed woman
Do you feel guilty after eating?
pacemaker next to xray
Treatment options.
caregiver with parent
10 tips for daily life.
birth control pills
Which kind is right for you?

Women's Health Newsletter

Find out what women really need.