Normally, when bleeding begins, a complex series of chemical events produces a "plug" to stop the bleeding; this plug is called a fibrin clot. The fibrin clot is the end-product of many different "clotting factors" reacting in the blood. Hemophilia is an inherited condition in which one of these clotting factors (factor VIII or IX) is absent from the blood, so that it does not clot normally. If your health care provider suspects that you have hemophilia, you may be given blood tests to examine how...
Hemophilia A -- also called classic hemophilia -- is most common and occurs in about 80% of people with hemophilia.
Hemophilia B -- also called Christmas disease -- is less common and occurs in about 20% of people with hemophilia.
Hemophilia A results from too little of a plasma protein called factor VIII, which helps blood clot. The greater the deficiency, the more severe the symptoms.
Mild hemophilia: 5% to 40% of the normal factor VIII level
Moderate hemophilia: 1% to 5% of the normal factor VIII level
Severe hemophilia: Less than 1% of the normal factor VIII level
Most people who have hemophilia A have moderate or severe symptoms.
Hemophilia B results from too little of a plasma protein called factor IX, which helps blood clot. As in hemophilia A, hemophilia B can be mild, moderate, or severe. The greater the deficiency, the more severe the symptoms.
If there is no family history of hemophilia, an infant would not be tested for the condition. However, if there is a family history of hemophilia, specific tests can be done from an umbilical cord blood sample to see if a newborninfant has hemophilia. In fact, if the family desires, such testing can be done before a child is born.
For moderate or severe hemophilia, doctors and caregivers usually don't see any signs of the condition at birth or even for some time afterward. Symptoms in children may include:
For mild hemophilia, you may not have any noticeable symptoms until you undergo a dental procedure, which may cause you to bleed heavily, or you may not have any unusual bleeding unless you are injured in an accident or have surgery.