At this time, there is no simple way to prevent hemophilia in someone who inherits a defective gene and thus produces too little clotting factor. If hemophilia runs in your family, you can be tested to see whether you carry the defective gene and receive counseling about your chance for having children with hemophilia.
Gene therapy clinical trials began in early 1999 in an attempt to cure hemophilia, and in vitro fertilization may allow selection and implantation of embryos that lack the hemophilia gene; but these are still considered experimental.
The proposed revised World Health Organization criteria for the diagnosis of polycythemia vera (p. vera) requires two major criteria and one minor criterion or the first major criterion together with two minor criteria.
Hemoglobin of more than 18.5 g/dL in men, 16.5 g/dL in women, or elevated red cell mass greater than 25% above mean normal predicted value.
Presence of JAK2 617V greater than F or other functionally similar mutations, such as...