Understanding Mononucleosis -- Symptoms

What Are the Symptoms of Mononucleosis?

The early symptoms of mononucleosis resemble those of the flu, including:

• Severe fatigue
• Headache
• Sore throat, which sometimes can be very severe
• Chills, followed by a fever
• Muscle aches

After a day or two, these additional symptoms of mono may occur:

• Swollen lymph nodes.
• Jaundice (a yellow tinge to the skin and eyes).
• A measles-like skin rash anywhere on the face or body; sometimes the rash develops suddenly after taking amoxicillin for a severe sore throat.
• Tiny red spots or bruise-like areas inside the mouth, especially on the roof of the mouth (palate).
• Soreness in the upper-left abdomen, from an enlarged spleen.

Call Your Doctor About Mononucleosis if:

• You have been experiencing mono symptoms -- especially for longer than 10 days -- or you have a severe sore throat for more than a day or two. You need to be examined by a doctor to rule out other illnesses, such as strep throat.
• You develop swollen lymph nodes all over your body, which may be a sign of some other illnesses like cancer or HIV (human immunodeficiency virus).
• You develop severe abdominal pain, which may indicate a ruptured spleen. Seek emergency medical treatment immediately.
• You have both a rash and headache, which might be signs of meningitis.
• You develop a rash consisting of many tiny red spots (called petechiae), which could be a sign of a low platelet count or other serious illness such as meningitis.