Uric Acid in Urine
What Affects the Test
Failing to collect exactly 24 hours of urine during a
uric acid urine test can cause inaccurate test results.
High uric acid levels may be caused
- Individual differences in the way your body
produces or gets rid of uric acid.
- Conditions, such as:
- Kidney disease or kidney
- The increased breakdown of body cells that occurs with some
types of cancer (including
multiple myeloma) or cancer treatments,
sickle cell anemia, or
- Other disorders, such as
preeclampsia, liver disease (cirrhosis),
hypothyroidism, and low blood levels of
- A rare inherited gene disorder called Lesch-Nyhan
- Medicines, such as some
diuretics, vitamin C (ascorbic acid), lower doses of
aspirin (75 to 80 mg aspirin daily), niacin, and some medicines used to treat
leukemia, lymphoma, or
Contrast material used for some
- Eating foods that are very high in
purines, such as organ meats (liver, brains), red
meats (beef, lamb), game meat (deer, elk), and some seafood (sardines, herring,
- Drinking a lot of alcohol, especially beer.
Low uric acid levels may be caused
Gout, when uric acid production is normal but
uric acid removal by the kidneys is reduced.
- Kidney damage or
disease that prevents the kidneys from filtering uric acid out of the blood
into the urine.
Folic acid deficiency or lead
- Not eating enough protein.
- Some medicines, such as allopurinol,
insulin, some diuretics, and high levels of aspirin.
alcohol during the collection period.
WebMD Medical Reference from Healthwise
June 12, 2012
This information is not intended to replace the advice of a doctor.
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