Uric Acid in Urine
What Affects the Test
Test results might not be accurate if you don't collect exactly 24 hours of urine.
There are many things that can cause your level of uric acid to be too high or too low.
High uric acid levels may be caused by conditions such as:
Kidney disease or kidney damage.
- Some types of cancer (including leukemia, lymphoma, and multiple myeloma) or cancer treatments.
Hemolytic anemia, sickle cell anemia, or heart failure.
- Disorders such as alcohol dependence, preeclampsia, liver disease (cirrhosis), lipid disorders, obesity, psoriasis, hypothyroidism, and low blood levels of parathyroid hormone.
- Starvation, malnutrition, or lead poisoning.
- A rare inherited gene disorder called Lesch-Nyhan syndrome.
High levels may also be caused by:
- Certain medicines. These include some diuretics, vitamin C (ascorbic acid), lower doses of aspirin (75 to 80 mg aspirin daily), niacin, and some medicines used to treat leukemia, lymphoma, and tuberculosis.
Contrast material used for some X-ray tests.
- Eating foods that are very high in purines. These include organ meats (liver, brains), red meats (beef, lamb), game meat (deer, elk), and some seafood (sardines, herring, scallops).
- Drinking a lot of alcohol, especially beer.
Low uric acid levels may be caused by:
- Kidney damage or disease.
Folic acid deficiency or lead poisoning.
- Not eating enough protein.
- Some medicines, such as allopurinol, insulin, some diuretics, and high levels of aspirin.
- Drinking alcohol during the collection period.
What To Think About
- Having a high uric acid level doesn't always mean you have gout. You won't need treatment as long as you don't have symptoms.
- If you have kidney disease or have had a problem with kidney stones, your doctor may start treatment with a medicine, such as allopurinol, even if your uric acid levels are not too high.
- A person with tophi or uric acid kidney stones will be treated for high uric acid levels no matter what the results of the uric acid test are.
- Uric acid also may be measured in blood. To learn more, see the topic Uric Acid in Blood.
WebMD Medical Reference from Healthwise
September 09, 2014
This information is not intended to replace the advice of a doctor.
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