Uric Acid in Urine
What Affects the Test
Test results might not be accurate if you don't collect exactly 24 hours of urine.
There are many things that can cause your level of uric acid to be too high or too low.
High uric acid levels may be caused
by conditions such as:
Kidney disease or kidney
types of cancer (including
multiple myeloma) or cancer treatments.
sickle cell anemia, or
heart failure. Disorders such as
preeclampsia, liver disease ( cirrhosis),
hypothyroidism, and low blood levels of
parathyroid hormone. Starvation,
lead poisoning. A rare inherited gene disorder called Lesch-Nyhan
High levels may also be caused by:
Certain medicines. These include some
diuretics, vitamin C (ascorbic acid), lower doses of
aspirin (75 to 80 mg aspirin daily), niacin, and some medicines used to treat
leukemia, lymphoma, and
Contrast material used for some
X-ray tests. Eating foods that are very high in
purines. These include organ meats (liver, brains), red
meats (beef, lamb), game meat (deer, elk), and some seafood (sardines, herring,
scallops). Drinking a lot of alcohol, especially beer.
Low uric acid levels may be caused
Gout. Kidney damage or
Folic acid deficiency or lead
poisoning. Not eating enough protein.
Some medicines, such as allopurinol,
insulin, some diuretics, and high levels of aspirin. Drinking
alcohol during the collection period.
What To Think About
Having a high uric acid level doesn't always mean you have
gout. You won't need treatment as long as you don't have symptoms. If you have kidney disease or have had a
problem with kidney stones, your doctor may start treatment with a medicine,
such as allopurinol, even if your uric acid levels are not too
A person with tophi or uric acid kidney stones
will be treated for high uric acid levels no matter what the results of the
uric acid test are.
Uric acid also may be measured in blood. To learn more, see the topic
Uric Acid in Blood.
WebMD Medical Reference from Healthwise
September 09, 2014
This information is not intended to replace the advice of a doctor.
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