ADHD Medication Chart
Class | Drug Name | Form | Duration | Common Side Effects |
Amphetamine Stimulants | Adderall | Short-acting | 4-6 hours | Some loss of appetite, weight loss, sleep problems, irritability, tics. Short-acting medicines require frequent dosing. |
Dexedrine | Short-acting | 4-6 hours | ||
Dextrostat | Short-acting | 4-6 hours | ||
Dexedrine Spansule | Long-acting | 6-8 hours | Some loss of appetite, weight loss, sleep problems, irritability, tics. Long-acting medicines are convenient but may have greater effects on appetite and sleep. | |
Adderall XR | Long-acting | 8-12 hours | ||
Vyvanse | Long-acting (prodrug) | 10-12 hours | ||
Methylphenidate Stimulants | Focalin | Short-acting | 4-6 hours | Some loss of appetite, weight loss, sleep problems, irritability, tics. Short-acting medicines require frequent dosing. |
Methylin | Short-acting | 3-4 hours | ||
Ritalin | Short-acting | 3-4 hours | ||
Metadate ER | Intermediate-acting | 6-8 hours | Some loss of appetite, weight loss, sleep problems, irritability, tics. Longer-acting medicines are convenient but may have greater effects on appetite and sleep. | |
Methylin ER | Intermediate-acting | 6-8 hours | ||
Ritalin SR | Intermediate-acting | 4-8 hours | ||
Metadate CD | Intermediate-acting | 8-10 hours | ||
Ritalin LA | Intermediate-acting | 8-10 hours | ||
Concerta | Long-acting | 10-12 hours | Some loss of appetite, weight loss, sleep problems, irritability, tics. Longer-acting medicines are convenient but may have greater side effects on appetite and sleep. | |
Quillivant XR | Long-acting | 8-12 hours | ||
Focalin XR | Long-acting | 6-10 hours | ||
Daytrana patch | Long-acting | 10-12 hour | Skin irritation, some loss of appetite, weight loss, sleep problems, irritability, tics. | |
Non- stimulants | Strattera(atomoxetine) | Long-acting (extended release) | 24 hours | Sleep problems, anxiety, fatigue, upset stomach, dizziness, dry mouth. Rarely, liver damage. There are some concerns about a link between Strattera and suicidal thoughts. |
Intuniv (guan- | Long-acting (extended release) | 24 hours | Sleepiness, headache, fatigue, abdominal pain. Rarely, Intuniv can cause low blood pressure and heart rhythm changes. | |
Antidepressants | Wellbutrin | Short-acting | 4-5 hours | Sleep problems, headaches. Although rare, Wellbutrin may increase the risk of seizures. |
Wellbutrin SR | Sustained release (long-acting) | 12 hours | ||
Wellbutrin XL | Extended release (long-acting) | 24 hours | ||
Tofranil | NA | 8-24 hours | Sleep problems, anxiety, fatigue, upset stomach, dizziness, dry mouth, elevated heart rate, risk of heart arrhythmias. | |
Pamelor | NA | 8-24 hours | ||
Aventyl | NA | 8-24 hours | ||
Norpramin | NA | 8-24 hours | Not recommended for children. Associated with cases of fatal heart problems. | |
Blood Pressure Medicines | Clonidine
Catapres or
Kapvay | NA | 4-6 hours (tablets) 24 hours (patch) 24 | Fatigue, dizziness, dry mouth, irritability, behavior problems, low blood pressure. Stopping this medicine suddenly can result in high blood pressure. |
Tenex (guan- facine) | NA | 6-8 hours | ||
ADHD Medicines and Safety The FDA has issued a warning about the risk of drug abuse with amphetamine stimulants. FDA safety advisors are also concerned about the possibility that all amphetamine and methylphenidate stimulants used for ADHD may increase the risk of heart and psychiatric problems. | ||||
WebMD Medical Reference


