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Allergies Health Center

FDA Advisers: Pill for Ragweed Allergy Safe and Effective

Placed under the tongue, it helps the body immunize itself against the offending plant
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WebMD News from HealthDay

By Steven Reinberg

HealthDay Reporter

TUESDAY, Jan. 28, 2014 (HealthDay News) -- Ragweed sufferers, take heart: A U.S. Food and Drug Administration advisory committee ruled Tuesday that a novel drug to combat this annual scourge is safe and effective.

If approved by the FDA, the drug -- Ragwitek, which comes in a pill form -- could offer a respite for the millions of Americans who suffer from ragweed allergy.

The brainchild of Merck & Co., Ragwitek is made of ragweed pollen and helps the body become immune to it. Patients begin taking the pill, which is placed under the tongue, 12 weeks before the ragweed pollen season begins and continue taking it through the season's end. In the United States, the ragweed season usually starts in September and runs through the fall.

People suffering from ragweed allergy suffer stuffy noses with sneezing, itching and congestion, as well as itchy and watery eyes. These annoying symptoms can affect quality of sleep and hamper daily activities. Plus, these problems often precede the development of asthma.

Current treatments include a variety of nasal sprays, as well as shots specifically tailored to tame all of a patient's allergies.

Dr. Len Horovitz, a pulmonary specialist at Lenox Hill Hospital in New York City, has his doubts about the power of this new pill. He said people who are allergic to ragweed often are allergic to other plants as well.

"I am skeptical that the pill will work on these other plant allergies," he said.

Another expert, however, said he sees this as a first step in making this kind of allergy treatment a possibility.

"The whole idea of [under-the-tongue] immunotherapy has been in the background for some time," said William Blouin, an allergy and immunology nurse practitioner at Miami Children's Hospital. "Until this point, immunotherapy has to be done as a series of injections."

A pill would make life simpler, he said, because it wouldn't require the inconvenience of weekly doctor visits or the pain of injections. Blouin said the new pill is intended only for ragweed, so if a person were allergic to other plants it would mean taking a separate pill for each one.

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