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Oral Immunotherapy for Allergies

Reviewed By: Andrew Seibert,

SOURCES: 2010 Medical Reference from Medstar Television. Deborah Gentile, M.D., Allergy/Asthma Specialist, Allegheny General Hospital, West Penn Allegheny Health System, Pittsburgh, PA.

© 1999-2011 Medstar Television

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Narrator:

As a coach and a dad, Mark Knochel (kah NOCK ull) loves playing sports with his kids, except during allergy season.

Mark Knochel:

Basically, like a scratchy throat, runny nose, teary eyes, things like that, just itchy from here to down here.

Narrator:

So when he heard about a study that could ease his allergies without shots, he was game.

Deborah Gentile, M.D.:

Sublingual immunotherapy is basically taking that same allergenic chemical or extract and instead of having the dose via a shot, you actually dose, in this case, sublingually, which is under the tongue in a drop form.

Narrator:

The blood vessels under the tongue quickly absorb the allergen extract.

Deborah Gentile, M.D.:

You don't really want to swallow it because what you're allergic to is typically a protein product and it will be dissolved in your digestive enzymes, so that's why it's not a pill that you swallow.

Narrator:

In this ragweed study, a-third received low dose drops, a-third got high dose drops, and a-third received no-dose, or placebo drops.

Deborah Gentile, M.D.:

And basically, we saw an improvement in the symptoms of allergies due to ragweed in both treatment groups, both the low dose as well as the high dose.

Narrator:

If this type of therapy is approved, Doctor Gentile (JENN tile) says patients could self-treat at home leading up to and during allergy seasons.

Deborah Gentile, M.D.:

Now if you're interested in getting long-term remission, or you know, a cure of your symptoms, you're most likely going to need to treat year-round with it for three to five years, just like the shots.

Narrator:

Giving patients a 'no-shot' alternative to control their allergies. For WebMD, I'm Sandee Lamotte.

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