Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Alzheimer's Disease Health Center

Font Size

Sugar & Alzheimer's: Are They Linked?

In Small Study, Sugar-Fed Mice Showed More Evidence of Plaques in Brain
WebMD Health News
Reviewed by Louise Chang, MD

Dec. 7 2007 -- Drinking too many sugary sodas may increase a person's risk for developing Alzheimer's disease late in life, new research suggests.

The small study was conducted in mice, not humans, and it falls far short of proving a link between the consumption of sugary beverages and Alzheimer's.

But study co-author Ling Li, DVM, PhD, of the University of Alabama at Birmingham says the findings add to the evidence implicating poor diet as a risk factor for Alzheimer's risk.

The mice were fed either water or sugar water equivalent to five cans of regular soda a day for a human.

The brains of the mice fed sugar water had more evidence of Alzheimer's disease than mice fed regular water.

"We are not saying that people who drink five cans of soda a day will get Alzheimer's," Li tells WebMD. "But there are many good reasons to limit sugar and sugary soft drinks, and this may be one more."

Diet and Alzheimer's

The study included specially bred mice genetically predisposed to develop symptoms similar to Alzheimer's in adulthood.

Over 25 weeks, eight of the mice received a regular diet, consisting of feed and regular water. Seven other mice ate the same feed, but they drank a water/sugar solution, and 43% of their overall caloric intake was from sugar.

The sugar-fed mice gained about 17% more weight over the course of the study. They also had higher cholesterol and were more likely to develop insulin resistance, a hallmark of diabetes.

These mice also performed worse than non-sugar-fed mice on some tests designed to measure learning and memory retention.

The brains of the sugar-fed mice had about twice as many plaque deposits as the mice fed regular water.

The study is published in the latest issue of the journal Biological Chemistry.

Study Proves Little, Critic Says

The researchers say the study provides compelling early evidence of a link between high sugar consumption and Alzheimer's disease.

"Our findings are of tremendous importance given that the consumption of sugar-sweetened beverages has increased dramatically in the past decades and will most likely remain high in modern societies," they write.

Today on WebMD

Remember your finger
When it’s more than just forgetfulness.
senior man with serious expression
Which kinds are treatable?
senior man
Common symptoms to look for.
mri scan of human brain
Can drinking red wine reverse the disease?
eating blueberries
Colored mri of brain
Close up of elderly couple holding hands
mature woman
Woman comforting ailing mother
Senior woman with serious expression