It is possible that the main title of the report Alzheimer's Disease is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Amyloid plaques are clumps of a protein called beta amyloid. This plaque builds up around the cells in the brain that communicate with each other.
Neurofibrillary tangles are made from a protein called tau. Normally, the tau protein helps cells communicate in the brain. In Alzheimer's disease, the tau protein twists and tangles. The tangles clump together, and some nerve cells die, which makes communication in the brain much harder.
As brain cells die, it shrinks. The damage to the brain eventually causes problems with memory, intelligence, judgment, language, and behavior.
Experts don't know if amyloid plaques and neurofibrillary tangles are side effects of Alzheimer's disease or part of the cause. These plaques and tangles are not found in people who do not have the disease.
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WebMD Medical Reference from Healthwise
November 14, 2014
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