Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Anxiety & Panic Disorders Health Center

Font Size

Natural Anxiety Treatment May Work

By Dianne Partie Lange
WebMD Health News

Feb. 25, 2000 (Lake Tahoe, Calif.) -- Kava, an extract from the root of the pepper plant Piper methysticum, has come a long way from the South Pacific, where it has been a staple of traditional medicine for centuries. Today in the U.S., kava is an herbal best seller, often taken for its relaxing properties. Now a review of studies from Europe and the U.S. concludes that kava is relatively effective and safe.

Max H. Pittler and Edzard Ernst of the University of Exeter in England write in the February issue of the Journal of Clinical Psychopharmacology that many studies of kava extract may have overestimated its beneficial effects. So they reviewed published studies on kava and asked kava experts to submit their research for evaluation. Pittler and Ernst focused on seven of the more carefully designed studies, three of which compared kava's effects to those of a placebo. In all three trials, kava was more effective than the sugar pill in relieving symptoms of anxiety.

Five of the seven trials reported adverse effects such as stomach complaints, restlessness, drowsiness, tremor, headache, and tiredness. But the two studies that reported no adverse effects represented 31 percent of the total number of patients tested, the authors write.

The authors pointed out several shortcomings of their research: The European medical journals might be underrepresented in the literature they searched. Researchers tend not to publish trials with negative results, particularly in journals of complementary or alternative medicine. And the sample size in most of the trials was small.

The sample size is one of several concerns of Naresh Emmanuel, assistant professor of psychiatry at the Medical University of South Carolina in Charleston, who reviewed the analysis for WebMD. He says none of the studies surveyed involved enough people to rule out the likelihood that the results were reached by chance.

Emmanuel also says that the range of anxiety symptoms in the study subjects was too diverse. "It's like saying, we'll take everybody with headaches. ... You're not looking at a unified sample," he tells WebMD.

Still, Emmanuel says, the bottom line is that the studies suggest kava is effective, and he occasionally suggests it to his patients. But he cautions people who take the supplement not to mix it with alcohol or other drugs that affect the brain, and not to do anything that requires being alert, such as driving. Also, if used for a long time, kava can cause scaling of the skin, he says.

Today on WebMD

young leukemia patient
Unhappy couple
embarrassed woman
Phobias frightened eyes
stressed boy in classroom
Distressed teen girl in dramatic lighting
man hiding with phone
chain watch