Dupuytren's disease most commonly
affects people of northern European heritage. It is rare in people of African
or Asian descent. Heredity is thought to be a factor, because Dupuytren's
disease tends to occur most often among close family members.
risk of Dupuytren's disease increases with age. It occurs most often in people
age 50 and older.1 Men are 7 to 15 times more likely
than women to have severe Dupuytren's disease that requires surgical treatment.
Older women often develop a milder form of the disease.2 Dupuytren's disease is very rare in children.
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Up to 30% of men older than 65 with a Northern European genetic
background will have Dupuytren's disease.3 Many of
these will not need treatment.
American Academy of Orthopaedic Surgeons and American
Academy of Pediatrics (2005). Dupuytren disease. In LY Griffin, ed.,
Essentials of Musculoskeletal Care, 3rd ed., pp.
331-332. Rosemont, IL: American Academy of Orthopaedic Surgeons.
Saar JD, Grothaus PC (2000). Dupuytren's disease: An
overview. Plastic and Reconstructive Surgery, 106(1):
Brown AN, Gilkeson GS (2005). Fibrosing diseases:
Diabetic stiff hand syndrome, Dupuytren's contracture, palmar and plantar
fasciitis, retroperitoneal fibrosis, and Peyronie's disease. In WJ Koopman, LW
Moreland, eds., Arthritis and Allied Conditions: A Textbook of Rheumatology, 15th ed., vol. 2, pp. 2093-2108. Philadelphia: Lippincott Williams and Wilkins.
Primary Medical Reviewer
Anne C. Poinier, MD - Internal Medicine
Specialist Medical Reviewer
David Pichora, MD, FRCSC - Orthopedic Surgery
May 4, 2010
WebMD Medical Reference from Healthwise
May 04, 2010
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