Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Psoriatic Arthritis Health Center

Font Size

Psoriasis Drug May Ease Psoriatic Arthritis

Ustekinumab Isn't Approved Yet but May Treat Psoriatic Arthritis
WebMD Health News
Reviewed by Louise Chang, MD

Feb. 12, 2009 -- Ustekinumab, a biologic drug designed to treat psoriasis, may also curb psoriatic arthritis, researchers report online in The Lancet.

Ustekinumab isn't on the market. Its maker, Centocor Inc., had asked the FDA to consider approving ustekinumab to treat chronic moderate to severe plaque psoriasis in adults. The FDA wants more information before making a decision, according to a news release Centocor issued in December 2008.

In The Lancet, researchers including Alice Gottlieb, MD, of Tufts Medical center in Boston report that ustekinumab trumped a placebo at treating psoriatic arthritis in adults studied for 36 weeks.

"Ustekinumab significantly reduced signs and symptoms of psoriatic arthritis and diminished skin lesions compared with placebo, and the drug was well tolerated," Gottlieb and colleagues write.

"Adverse events and infections were similar in each treatment group and serious adverse events arose only with the placebo," the study states. But the researchers caution that larger, longer studies are needed to further study ustekinumuab for the treatment of psoriatic arthritis.

Centocor funded the study, and several of Gottlieb's colleagues are Centocor employees.

Ustekinumab looks like "an attractive option in psoriatic arthritis," states an editorial published with the study. But "we should, nevertheless, remain vigilant for potential complications," write the editorialists, who included Raquel Cuchacovich, MD, of the rheumatology section of the Louisiana State University Health Sciences Center in New Orleans.

Today on WebMD

5 Types Of Psoriatic Arthritis
Psoriasis Overview
Pain Tips
young woman touching skin
Woman rubbing shoulder
Psoriasis Laser Therapy
Psoriatic Arthritis Do You Know The Symptoms
Woman scratching shoulder
Health Check