Steroids (short for corticosteroids) are synthetic drugs that closely resemble cortisol, a hormone that your adrenal glands produce naturally. Corticosteroids are different from the male hormone-related steroid compounds that some athletes use.
Steroids work by decreasing inflammation and reducing the activity of the immune system. Steroids are used to treat a variety of inflammatory diseases and conditions.
Ankylosing spondylitis is a form of arthritis that mainly targets the spine. Over time, ankylosing spondylitis can cause your spine to become stiffer, and eventually the vertebrae (bones in your spine) may fuse together. People have a tendency to develop a stooped posture as the disease progresses. It is one of a group of diseases called spondyloarthropathies that affects about 2 to 5 people out of 1,000.
Other joints areas that can be affected include shoulders, hips, and often tendons connected...
Steroid drugs are available in several forms that vary in how easily they dissolve or how long they stay in the body.
Steroids may be given systemically, which means throughout the "system" or body, or locally to the precise place where a problem exists.
Systemic steroids can be given either through a vein (intravenously, or IV), into a muscle (intramuscularly), or by mouth (orally). Local steroids can be given as eye drops, ear drops, and skin creams, or by direct injection into joints, bursae (lubricating sacs between certain tendons and the bones beneath them), or around tendons and other soft tissue areas.
Why Are Steroids Injected?
Injecting steroids into one or two local areas of inflammation allows doctors to deliver a high dose of medication directly to the problem area. When doctors give steroids by mouth or intravenously, they cannot be sure an adequate amount of the steroid will eventually reach the problem area.
What Conditions Are Treated With Steroid Injections?
Steroids are often injected directly into joints to treat conditions such as rheumatoid arthritis, gout, or other inflammatory diseases. Steroids also can be injected into inflamed bursae, or around tendons near the shoulder, elbow, hip, knee, hand, or wrist.
The decision to prescribe steroids is always made on an individual basis. Your doctor will consider your age, level of physical activity, and other medications you are taking. Your doctor also will make sure you understand the potential benefits and risks of steroid injections.
When Should Steroid Injections Not Be Used?
Steroids should not be injected when there is infection in the area to be injected or elsewhere in the body. If a joint is already severely destroyed, injections are not likely to provide any benefit.
If a patient has a potential bleeding problem or is taking anticoagulants (often referred to as blood thinners), steroid injections may cause bleeding at the site. For these patients, injections are given only with great caution.
Frequent steroid injections, more often than every three or four months, are not recommended because of the increased risk of weakening tissues in the treated area.