Scleroderma (pronounced SKLEER-oh-der-ma) is a disease that affects your skin. When you have scleroderma, your skin gradually tightens and thickens or hardens. It can’t stretch like it used to.
Scleroderma can also change tiny blood vessels. That damages internal organs. Although it usually affects the hands, face, and feet, it can also target the digestive tract, heart and blood flow, lungs, and kidneys.
Symptoms of gout usually strike unexpectedly. They typically do not last more than a week, but may recur. Although, less commonly, some patients may have chronic pain due to gout. Symptoms of a gout attack may include:
Sudden, intense pain in a joint, typically the big toe or ankle, sometimes the knee, hand, or wrist
Swelling, inflammation, and a feeling that the joint is very hot
Extreme tenderness of the joint to even the lightest touch
Red or purple skin around the joint