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Blood Thinner Doesn’t Prevent Miscarriages: Study

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Blood Thinners Not Needed? continued...

But there was no difference in the number of those complications between the two groups.

“We basically showed a daily injection of blood thinner throughout pregnancy is ineffective at preventing pregnancy complications,” Rodger says.

But women who took the blood thinner did have more minor bleeding, like nosebleeds, gum bleeds, and vaginal bleeds. They were also more likely to have allergic reactions to the medication.

And they had to suffer through the pain of daily injections in the stomach or thigh.

During the average pregnancy, a woman will need about 400 such injections at a cost of about $8,000 before insurance, Rodger says.

Blood Thinners 'Overprescribed'

“It is discouraging, but on the other hand, it saves a lot of women the burden of giving themselves injections, and now doctors can have evidence-based discussions instead of hope-based discussions with patients,” he says.

Other experts who were not involved in the research agree.

“I would like to think that it will change practice,” says Catherine Herway, MD, assistant director of obstetrics and maternal/fetal medicine at Staten Island University Hospital in Staten Island, N.Y.

Blood thinners, she says, are “way overprescribed in pregnancy.”

She says she sees many patients who are referred to her because tests show they have blood clotting genes but may not have a history of clots.

Those patients sometimes demand to be given heparin. “For some reason, they think it’s going to be the miracle drug that’s going to save their baby,” she says.

She says she hopes the study will help patients and doctors be more thoughtful about taking blood thinners.

Rodger says the study's results don’t apply to all women. He says that in women who’ve had a history of deep vein thrombosis -- blood clots in deep veins in the body -- and those with certain autoimmune diseases, there is some evidence that taking blood thinners during pregnancy can help. But he says those are relatively rare cases, and that most women, even if they’ve had several miscarriages, probably won’t benefit from the drugs.

Herway agrees: “It’s hard to tell patients no sometimes, but sometimes it’s in the patient’s best interest to do what science tells us to do.”

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