Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Health & Pregnancy

Font Size

Preeclampsia: Creatinine Clearance Test - Topic Overview

When muscles use energy, they release a waste product called creatinine into the blood. The kidneys then filter creatinine from the blood. From the kidneys, creatinine passes out of the body through the urinary tract. If the kidneys are not functioning normally, high amounts of creatinine remain in the blood while low amounts are passed out in the urine.

During a normal pregnancy, increased blood volume and kidney function cause an increase in the amount of creatinine filtered out of the blood and passed into the urine. A measurement of this amount is called the creatinine clearance value. If the kidneys are damaged by preeclampsia, the creatinine clearance value decreases because the kidneys are filtering less creatinine out of the blood. The amount of kidney damage can be estimated by the amount of decrease in the creatinine clearance value.

The creatinine clearance test requires a blood sample and a sample of all the urine collected for 24 hours (24-hour urine sample).

For more information, see the topic Creatinine and Creatinine Clearance.

    WebMD Medical Reference from Healthwise

    Last Updated: November 14, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
    Next Article:

    Preeclampsia: Creatinine Clearance Test Topics

    Pregnancy Week-By-Week Newsletter

    Delivered right to your inbox, get pictures and facts on
    what to expect each week of your pregnancy.

    Today on WebMD

    hand circling date on calendar
    Track your most fertile days.
    woman looking at ultrasound
    Week-by-week pregnancy guide.
    Pretty pregnant woman timing contaction pains
    The signs to watch out for.
    pregnant woman in hospital
    Are there ways to do it naturally?
    slideshow fetal development
    pregnancy first trimester warning signs
    What Causes Bipolar
    Woman trying on dress in store
    pregnant woman
    Close up on eyes of baby breastfeeding
    healthtool pregnancy calendar
    eddleman prepare your body pregnancy