Preterm Labor - Cause
Preterm labor can be caused by a problem involving the fetus, the mother, or both. Often a combination of several factors is responsible. But in about 1 out of 3 preterm births, the cause is not known.2
Causes of spontaneous preterm labor include:
- Women who are pregnant with more than one fetus have an increased risk of complications-both maternal and fetal-and typically deliver early. See the topic Multiple Pregnancy: Twins or More for more information.
- Infection, which can trigger uterine contractions and preterm premature rupture of membranes (pPROM).
- Placenta abruptio, the early separation of the placenta from the uterus. For more information, see the topic Placenta Abruptio.
- The use of drugs such as cocaine or methamphetamine.
- Problems with the uterus or cervix, such as a weak, thin cervix; fibroid growth; or an abnormally shaped uterus.
WebMD Medical Reference from Healthwise
Last Updated:
January 14, 2009
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