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A sculpted nose, wider eyes, smoother skin, perkier breasts, even a perfect smile . . . America's favorite wrinkle-zapper now claims to do it all. Is that a good thing?

By Sarah Z. Wexler

WebMD Feature from "Marie Claire" Magazine

Brave New Botox

Marie Claire magazine logo

Since it first hit the scene in 1989, Botox has gone through more reinventions than Madonna. Back then it was an ophthalmologic treatment for spastic eyelids, but it wasn't long before doctors noticed the smoothing side effects and started using it "off label" (for purposes other than the official FDA nod) in Canada. In 2002, the 'tox finally received FDA approval for treating wrinkles, kicking off the stateside face-freezing frenzy. Now it's the country's most popular cosmetic procedure and its second most recognized prescription name (after Viagra), pulling in an estimated $1.28 billion worldwide last year for its maker, Allergan. Yeah, the stuff is still ubiquitous as an antiager and medical fix-it, treating everything from migraines to "BlackBerry thumb." But with its bold new applications, Botox is making sure that even if the economy slumps, your face doesn't have to.

Wide Eyes

Most of us rely on eyeshadow and liner tricks to get that innocent, doe-eyed look, but some women are turning to dermatologists for a more intense fix. Many docs are injecting a minuscule amount of Botox into the center of the lower lashline's orbicularis oculi muscle to create "a widening of the eye and more of an almond shape," says Boston derm Dr. Ranella Hirsch, who performs the procedure. "It's especially popular with Asian women, but it's magnificent and very subtle on anyone." ($300 - $500)

Ski-Slope Nose

Changing your nose used to mean thousands of dollars in plastic-surgery bills and a pair of shiners. Though Botox can't do anything for the bridge, some doctors use it to give patients a perfect swoop - with no recovery time. Dr. Nodar Janas of MesoBoutique in Great Neck, NY, injects it into the bottom of the septum to lift the tip of the nose, a procedure he does for more than a dozen patients per month. You get "plastic-surgery results," he says, especially when combined with a filler like Juvéderm or Restylane. Other doctors, like NYC dermatologist Dr. Patricia Wexler, use Botox to make an upturned nose slope downward by injecting the nostrils. "The change is pretty dramatic in making a straighter nose," she says. "You can raise or lower the tip by about three millimeters." ($150 - $250)

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