Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Cosmetic Fillers and Wrinkles

Fat Injection Fillers

Ever wish you could move that fat from your thighs to somewhere it might look a little better? Fat injections involve removing small amounts of fat from the thighs, belly, or buttocks and injecting it under the skin of the face. The fat expands the skin, shrinking wrinkles. Because it is your own tissue, there can be no allergic reaction. Results vary and are sometimes permanent.

Poly-L lactic Acid (Sculptra) Fillers

When injected under the skin, poly-L lactic acid (PLLA) stimulates skin cells to make collagen. Poly-L lactic acid is nontoxic and has been widely used in suture material for years.

PLLA is FDA-approved for cosmetic treatment of certain skin conditions in people with HIV. It is often legally used "off-label" to treat wrinkles in otherwise healthy people. It's considered "semi-permanent," meaning results can last for months to years.

Calcium Hydroxylapatite (Radiesse) Fillers

In 2006, the FDA approved calcium hydroxylapatite for cosmetic injection. This cosmetic filler is made of the minerals that give bone its strength and texture. These minerals are ground into tiny particles and suspended in water solution, which is injected under the skin.

In the trial that led to its approval, calcium hydroxyapatite worked significantly better and lasted longer than collagen injections to reduce severe wrinkles.

Polymethyl methacrylate (PMMA) Fillers

Polymethyl methacrylate is a permanent cosmetic filler. Before the FDA approved it for that use, PMMA was already being used as a cement for bone surgery.

That's right -- we said "cement." Polymethyl methacrylate doesn't break down. So, unlike biological products, PMMA produces permanent cosmetic results.

URAC: Accredited Health Web Site TRUSTe online privacy certification HONcode Seal AdChoices