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Bipolar Disorder Health Center

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Bipolar Disorder: 'Atypical' Antidepressants for Bipolar Disorder

Newer "atypical" antidepressants work differently than other available antidepressants. Currently, none are approved by the FDA to treat bipolar depression. But some evidence suggests they may play a role in treating depression in bipolar disorder.

They include:

  • Wellbutrin (bupropion)
  • Effexor (venlafaxine)
  • Remeron (mirtazapine)
  • Serzone (nefazodone)

Studies have shown that Wellbutrin is effective when added to lithium therapy. However, findings on all of these drugs are still preliminary.

Reviewed by the doctors at The Cleveland Clinic Department of Psychiatry and Psychology.

WebMD Medical Reference provided in collaboration with the Cleveland Clinic

Edited by David H. Fram, MD on September 01, 2006
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