Calcium channel blockers block the small pores in cells that allow calcium to move in and out and widen blood vessels. It's not clear exactly how the drugs work, but they are used to lower blood pressure, improve irregular heartbeats, and treat migraines. They may also help stabilize moods.
The primary symptoms of bipolar disorder are periods of elevated or irritable mood accompanied by dramatic increases in energy, activity, and fast thinking. The illness has two (bi) strongly contrasting phases (polar): 1) bipolar mania or hypo-mania and 2) depression.
1) Bipolar mania or hypo-mania symptoms include:
Euphoria or irritability
Increased energy and activity
Excessive talk; racing thoughts
Unusual energy; less need for sleep
Sometimes, a headache can develop after taking certain calcium channel blockers. These headaches should gradually disappear once you have been taking the medication for a while. Talk to your doctor if headaches continue. Some people also report tenderness, swelling, or bleeding of the gums when starting to take calcium channel blockers. Regular brushing, flossing, and gum massages along with routine dental visits can help lessen this effect. As with any medication, it is important to see your doctor regularly to make sure the drug is working properly.
Calcium channel blockers tend to cause fewer serious side effects than some other drugs used to treat bipolar disorder. However, they are not as well studied and may not be effective.
Common calcium channel blocker side effects include:
SOURCES: WebMD Medical Reference: "Bipolar Disorder (Manic Depressive Disorder)." WebMD Assess Plus: Bipolar Disorder Assessment. National Institute for Mental Health: "Step-BD Womens Studies." Massachusetts General Hospital Bipolar Clinic & Research Program. MedicineNet.com: "Bipolar Disorder (Mania)." WebMD Medical Reference: "Effects of Untreated Depression." American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."