Bipolar disorder is a serious mood disorder that affects more than 10 million Americans. Unlike unipolar depression, bipolar disorder is equally common in men and women. The onset of the condition typically occurs in the early 20s, but (although rare) the first symptoms can appear in early childhood or late in life.
Although some people may have only one episode, bipolar disorder is a lifelong condition that usually involves recurrent episodes. It's usually marked by episodes of mania or hypomania...
Tricyclic antidepressants work by increasing levels of the mood chemicals serotonin and norepinephrine in the brain. However, because they may sometimes increase the risk of mania or rapid cycling -- as well as heart problems if you take heart medication -- these drugs are less often recommended for bipolar disorder.
SOURCES: WebMD Medical Reference with The Cleveland Clinic: "Bipolar Disorder (Manic Depressive Disorder)." WebMD Assess Plus: Bipolar Disorder Assessment. National Institute for Mental Health: "Step-BD Womens Studies." Massachusetts General Hospital Bipolar Clinic & Research Program. MedicineNet.com: "Bipolar Disorder (Mania)." WebMD Medical Reference with The Cleveland Clinic: "Effects of Untreated Depression." American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."