No one's mood is stable 100% of the time. It's normal to feel down when you hit a rough patch and elated when life goes your way.
But if you have bipolar disorder, the highs and lows are a lot more extreme, and they can sometimes seem random. The good news is that with treatment and some hard work, you can control the impact this disease has on your life.
Tricyclic antidepressants work by increasing levels of the mood chemicals serotonin and norepinephrine in the brain. However, because they may sometimes increase the risk of mania or rapid cycling -- as well as heart problems if you take heart medication -- these drugs are less often recommended for bipolar disorder.
WebMD Medical Reference with The Cleveland Clinic: "Bipolar Disorder (Manic Depressive Disorder)." WebMD Assess Plus: Bipolar Disorder Assessment. National Institute for Mental Health: "Step-BD Womens Studies." Massachusetts General Hospital Bipolar Clinic & Research Program. MedicineNet.com: "Bipolar Disorder (Mania)." WebMD Medical Reference with The Cleveland Clinic: "Effects of Untreated Depression." American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."
Joseph Goldberg, MD on October 18, 2014