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    Arachnoiditis

    Important
    It is possible that the main title of the report Arachnoiditis is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

    Synonyms

    • arachnitis
    • spinal arachnoiditis

    Disorder Subdivisions

    • adhesive arachnoiditis
    • arachnoiditis ossificans
    • hereditary arachnoiditis
    • neoplastic arachnoiditis
    • optochiasmatic arachnoiditis
    • postmyelographic arachnoiditis
    • rhinosinusogenic cerebral arachnoiditis
    • cerebral arachnoiditis

    General Discussion

    Arachnoiditis is a disease characterized by an acute inflammatory stage that occurs in the dura (exterior) and the arachnoid (interior), two of the three membranes that cover and protect the brain, the spinal cord and the nerve roots. The arachnoid contains the cerebrospinal fluid which circulates from the brain to the sacral area, about every two hours; it filters any invasion and usually responds first by inflammation and follows with a chronic stage life-lasting phase characterized by scarring and fibrosis. As a result, abnormal adhesion of nerve roots to the dural sac or to each other (clumping) occurs in a variety of configurations that alter significantly the function of the roots and the spinal cord. This causes a variety of neurological deficits and severe chronic neuropathic pain usually located in the area affected. In the pre-antibiotic era, severe cases of tuberculosis or syphilis invaded the spine causing arachnoiditis; currently these infections are rare, but it is important to mention that arachnoiditis will result in most patients affected by fungal meningitis from attempted epidural injections of tainted steroids.

    Resources

    American Chronic Pain Association
    P.O. Box 850
    Rocklin, CA 95677
    USA
    Tel: (916)632-0922
    Fax: (916)652-8190
    Tel: (800)533-3231
    Email: ACPA@theacpa.org
    Internet: http://www.theacpa.org

    BackCare, the Charity for Healthier Backs
    16 Elmtree Road
    Teddington, TW11 8ST
    United Kingdom
    Tel: 02089775474
    Fax: 02089435318
    Tel: 08451302704
    Email: info@backcare.org.uk
    Internet: http://www.backcare.org.uk

    National Spinal Cord Injury Association
    75-20 Astoria Blvd
    Jackson Heights, NY 11370
    USA
    Tel: (718)803-3782
    Tel: (800)962-9629
    Email: info@spinalcord.org
    Internet: http://www.spinalcord.org

    NIH/National Institute of Neurological Disorders and Stroke
    P.O. Box 5801
    Bethesda, MD 20824
    Tel: (301)496-5751
    Fax: (301)402-2186
    Tel: (800)352-9424
    TDD: (301)468-5981
    Internet: http://www.ninds.nih.gov/

    American Pain Society
    4700 West Lake Avenue
    Glenview, IL 60025
    Tel: (847)375-4715
    Fax: (866)574-2654
    Email: info@ampainsoc.org
    Internet: http://www.ampainsoc.org

    Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg, MD 20898-8126
    Tel: (301)251-4925
    Fax: (301)251-4911
    Tel: (888)205-2311
    TDD: (888)205-3223
    Internet: http://rarediseases.info.nih.gov/GARD/

    National Pain Foundation
    300 E. Hampden Ave.
    Suite 100
    Englewood, CO 80113
    USA
    Tel: (303)783-8899
    Fax: (303)692-8414
    Tel: (866)590-7246
    Email: npf@nationalpainfoundation.org
    Internet: http://www.nationalpainfoundation.org

    For a Complete Report:

    This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

    The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

    It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

    This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

    For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

    Last Updated: 1/14/2013
    Copyright 1988, 1990, 2000, 2013 National Organization for Rare Disorders, Inc.

    WebMD Medical Reference from the National Organization for Rare Disorders

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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